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  • maiarose3
    Wonder if anyone else is taking Celexa for depression and what your experiences have been?
  • Bobo
    Hey, I've been on citalopram (the generic Celexa) for about 14 months, and it's made a huge difference in my life. PCP required weekly visits with her for six weeks. Initial dosage was minimal and then raised as I was tolerating it well. I've been able to see both trees and forest in my life, and enjoy most days, rather than feeling far back in that dark cave. Thanks to all other responders-we learn from each other. 
  • charliegirl78
    Wonder if anyone else is taking Celexa for depression and what your experiences have been?
    I too have struggled with depression, even before the dx of MS.  I'm not taking Celexa, but just recently upped my dose of Zoloft for my emotional rollercoaster ride....It works, most of the time, but need to add something for depression (that's my opnion of myself anyway). just got a book on depression in MS patients (just got as in today).  Actually got it for free from an MS site called MS Active Source.  the book is called 'It's Not All in Your Head, Anxiety, Depression, Mood Swings and Multiple Sclerosis' .  I went to the site just to check out what info they offered, and was able to request this book and a Yoga dvd (specifically for MSers by MSers) for free.  Took about a week and a half for delivery.  I'm looking forward to reading it and maybe make sense of the emotional side of MS. I think we tend to focus more on the scary physical stuff and forget to take care of our mind and spirit.  Good luck to you with your medication and I look forward to reading some feed back so I can take it into consideration for the next doc appointment.
  • maiarose3
    Thanks, Lisa. I also had depression before MS (and a strong family history of it). It's hard to know what's triggered by the brain chemistry of MS, dealing with the symptoms & diagnosis, and the side  effects of meds. I've read that interferon directly depletes serotonin levels and learned after several suicidal bouts that Rebif is known for this (with no real warning from my neurologist, even though he knew my family history).
    Apparently, some Dr's think Celexa/citalopram (the generic) is comparable to Lexapro, but from reading comments online, a lot of patients think Lexapro is much better. Some also think that Celexa helps with anxiety, but not so much with depression, so I'll do some more research. I've been on Celexa (max dose) for 1 1/2 years now, but it seems my depression isn't lifting as of late.
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    Great tips and very easy to understand. This will definitely be very useful for me when I get a chance to start my blog Excellent Digitizing
  • maiarose3
    I hear ya, Charliegirl. Thanks for the good advice/resources. Right now I'm glad that my physical symptoms are under control, but the emotional ones are keeping me from working or having any kind of life. For me the fatigue, depression, and reverse sleep cycle are keeping me from living & I don't want to miss the spring & summer! I've talked to my PCP & neurologist recently and now will start meds for fatigue (amantadine) and have to decide 1) should I try a new anti-depressant 2) should I stop interferons (Rebif) which cause/add to the depression, or both. And then, what new MS meds do I try- Tysabri or Gilenya?, which both have major associated risks. Rebif has been working well with stopping my disease progression & maybe even shrinking lesions, but do I risk my mental health for this? So hard to know...I know we MSers all face these tough decisions...
  • arlawgirl
    My PCP prescribed Celexa minutes after he gave me my tentative diagnosis (I passed out, literally, in true Scarlett O'Hara fashion and he was very worried about my ability to handle the news).  I was SICK AS A DOG and stopped taking it.  I threw up, I felt dizzy, and I was MORE anxious and scared.  I am going to get a script for Zoloft since I've taken it before.  I think it's interesting that if you search Celexa on Google, the search engine suggests "Celexa half life" as one of the most-often searched phrases containing the word.  This means people are searching to find out how long the blasted stuff stays in your system since so many people have adverse effects.  I do hear, however, that some people tolerate it well.  If your doctor thinks it's right for you, give it a whirl, but if you start to have bad side effects, I would call in and request a new Rx.  There are so many SSRIs out there, you shouldn't have to deal with one that makes you feel crappy!
  • maiarose3
    Thanks for your replies! I tried Celexa after becoming suicidially depressed on Rebif, but the 1st dose made me feel sick & dizzy & really high, so I gave up and just took St. John's Wort for the first couple years after my diagnosis. I don't know if it did much besides making me extra sun-sensitive and it really is only for mild depression. I finally got a second opinion when I got worse again & she recommended Celexa just as my neurologist had, so I gave it another go. It's been working well & side-effect free (I think, though it's so hard to tell with MS symptoms & other meds & prior depression), but I'm wondering if it's time to switch to something stronger, since my PCP says I'm already on the maximum dose. Does anyone know if it's good to switch SSRI's for effectiveness?
  • arlawgirl
    Maiarose- I am sorry you have had a rough time in the past, but I was actually really pleased to hear that you recognized the depression side-effect of Rebif.  I have been terrified (starting Rebif this week) that I would become suicidally depressed on the medication and not realize that it was a side-effect.  I guess in my line of work I see people quite often with severe mental issues who think that they are in their right mind- and that suicide is really the right choice.  I will keep taking my SSRI and keep a close eye on myself!

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