Search Discussions

Main Content

  • johni619
    This is new to me and very surreal. I was first diagnosed in 2017 but shortly after became pregnant so my symptoms never were life changing. Recently I had two episodes which hospitalized me for weeks at time and realized that this was something serious. When I was first diagnosed they prescribed me tecfidera but I never took it because I knew I wanted to have a baby. This time around they suggested trying out rituxan and honestly after reading about it I'm scared. Does. Anyone know anything about rituxan?
  • maria1
    If this was me, I would compare the write ups for the 2017 diagnosis and a more recent report, what is the progress of the disease in two years, ten percent, twenty percent? What has changed in my life in the past two years that has negatively affected me, catastrophic events, major illness for family, financial woes divorce, etc. ms does not function in a void, what is negatively happening to us has an impact upon how the disease reacts. How old am I.

    Doctors sometimes use cancer drugs to treat ms, have you asked the doc why that was the choice above ms disease modifying treatments? That would have . to me, an impact upon my decision about the drug.

    I would need a clear picture of the impact ms is having on me before I made a choice. When I was diagnosed I was so sick I would try anything to get some relief.

    Having ms changes how the body acts about everything, the weather, a tooth ache, happy news. It is like jeckyll and hyde in the same body, the old me and the new me who I had to meet for the first time, like the first time I tried on high heels, I had to learn how to walk all over again.

    Some decisions are best made with counseling, have you considered analyzing your choices with a therapist, whatever you do, you will have to live with the rest of your life so choose with your best educated guess because it is only a guess, you have not been here before and you want to give yourself the best odds you can get. Delaying yes or no for a month wont make a big difference. Nobody knows their body will react to a drug, we have just a best educated guess, we have all been guinea pigs, making our own choices about what drugs to try for whatever symptoms we have, some of us guess based upon the side effects of the drug offered, some guess upon how awful we feel. Since we are members of an elite group we do not have a big arena to compare with. tens of millions of people smoked so they have tens of millions of examples of what cigarettes do to a person, we dont have that large a group to compare the actions of the drugs. I know this is not much help but it is important for you to know that you need all the information and time you need to choose. We can listen and we can comment but it is you who get to make the choice. Talking it through with us will help, and with your spouse and with your doctor, be like a kid, remember to ask WHY? maria
  • heymanhowsitgoing
    It looks like Rituxan is a B cell-depleting therapy. Maybe check with your neuro to see if plasmapharesis would be a good option as a way of testing the waters? Because plasmapharesis clears out a lot of the antibodies and proinflammatory chemical signaling molecules that B cells produce, it should be effective if B cells are a primary driver of damage in your particular case.

    I would think that if plasmapharesis is effective, that's a good indication that Rituxan would be as well.