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  • Summer1
    Hello everyone, Copaxone and the generics has been my first and only DMD I have tried since the beginning of my diagnosis. When I was on Copaxone I had no problems at all. Then switched to generics and get REALLY bad side effects. It happens seconds after I inject I get heart pounding rapidly and flushing. I've heard of the "immediate injection reaction" but I don't think its normal if it happens every single time .  I'm afraid of switching to a different DMD because of serious side effects like PML. Abagio I guess I have considered but read about it and saw that it can cause heart infections and issues.  Other then the "heart attack feeling" that copaxone generic causes me, it has kept me relapse free!! I'm not sure what to do. Can anyone share they're experience with DMD's or perhaps some are trying something more natural like no medications and exercise and eating healthy instead ? Has this worked for anyone? 
  • jasonprestovfd
    I had good luck with Avanox for 4 years, then I started getting the flu like symptoms to the point that the day after my injection I would practically stay in bed. It took about 6 months to figure out what was going on and change to tysabri. It took me awhile to put the risk of PML in God's hands. I've been on it for about four and a half years with no issues. 
    I hopyhope you find something that works for you. 
    Please keep us posted on  how you are doing 
  • golgotha
    Other then the "heart attack feeling" that copaxone generic causes me, it has kept me relapse free!!


    Copaxone has been shown (it's one of the "older" DMTs so it has a long track record of stats) to do nothing in about 1/3 of people using it. I was diagnosed in my late 20s, back in the "stone age" of MS before there were any DMTs. As such, I was on nothing for a couple of decades. I had no major attacks in that time (nothing like my first attack).

    So with that said, the fact that you have had no attacks, I'd ask is it due to Copaxone or just good luck? Food for thought.

    But with that said, if the "leaky pool" model/theory is correct, the disease is still advancing in you regardless of whether you "feel" it or not (the idea is that MRIs don't pick up everything that's happening). So with that idea in mind...

    Can anyone share they're experience with DMD's


    The only other one I've been on is Ocrevus. That stopped a case of "active MS" that could be seen on MRIs and I've had no problems with it.

    I know one MSer who was on it in the Ocrevus trial before it was FDA approved. She gets lots of side effects but still stays on it because she gets even worse side effects on other DMTs.

    or perhaps some are trying something more natural like no medications and exercise and eating healthy instead ?


    As mentioned above, spending 15 or 20 years not being on a DMT or medications, I tried many alternative ideas. In hindsight, if I had the chance to do it over and had access to the range of DMTs that are available now, I'd go the DMT route.