I had my first MS flare when I was 11. I am now 54, having finally been diagnosed in 2001. Tysabri has literally been a lifesaver. I have limped the gauntlet so to speak and haven't given up, although I am sooooo over this disease...enough already. It affects everything in my life but I am thankful I have the level of functioning that I do have. Also I have a wonderful partner who is completely supportive and that has made all the difference in my life.