Initial flare [optic neuritis - left eye] hit at the end of February 2000. After giving copious amounts of blood to be tested for every.freaking.thing, was given "possible MS" as my Dx in March 2000. Had another flare that August [right arm numbness] that solidified my Dx. Have been on Rebif, Betaseron and most recently Copaxone. But, most recent MRI shows two new lesions while on Copaxone, am smack dab in the middle of a flare that is causing gait difficulty for both legs, and will most likely be going on Tysabri once this exacerbation is under control.