Yes! I do. A recent relapse temporarily took me out of commission but I'm working my way back up to my original speed and distance (a few 3-4 mile runs per week). For me, running has played a huge role in regaining mobility post-relapse, even if things are a little different now. There are MSers who do road races, even marathons, and some who do ultramarathons. So if you want to run again, go for it! You probably won't regret trying, but you'll definitely regret not having tried.